The market for AMD is driven by increasing number of AMD patients throughout the world. According to the American Academy of Ophthalmology, in the U.S., around 11 million patients are affected by AMD and the prevalence of AMD is high in countries in Southeast Asia and sub-Saharan Africa, due to deficiency of vitamin A in these countries.
Growing reimbursement benefits for AMD drugs is another major driver for the age-related macular degeneration market. Depending on regular cost of the drug, Medicare postulated a National Reimbursement Rate in the U.S. In this condition, the agency pays almost 80% of the cost of bevacizumab and ranibizumab injections and the remaining 20% of the cost is co-paid. Medicare part B is a medical insurance, which includes insurance for eye diseases and diagnostic tests that also covers specific treatment conditions such as AMD. Lack of trained ophthalmologists, high cost of drugs for wet AMD, and associated high risk are some major challenges before the AMD market.
The age-related macular degeneration market can be broadly categorized on the basis of type of AMD, type of drug, route of administration, and geography. Based on type of AMD, the market can be segmented into wet AMD and dry AMD. Based on type of drug, it can be divided into Lucentis, Eylea, Avastin, Visudyne, and others. Based on route of administration, the market has been segmented into IV and intravitreal. Based on geography, the global AMD market can be divided into four regions viz. North America, Asia Pacific, Europe, and Rest of World.
Major players operating in the age-related macular degeneration market are Genentech, Inc. (a member of Roche Group), Pfizer, Inc., Valeant Pharmaceuticals International, Inc., Regeneron Pharmaceuticals, Bayer Healthcare (a subsidiary of Bayer AG), and Novartis AG.